KininsMichael Bader Walter de Gruyter, 30 בנוב׳ 2011 - 386 עמודים This handbook of kinin biology and biochemistry covers the current knowledge of kinins, a family of peptides involved in numerous physiological and pathophysiological processes. Recent publications have shown that the kinin system is highly relevant in a variety of disease states such as diabetes, multiple sclerosis and traumatic injuries. Furthermore, the first drug targeting system has just been approved for clinical use. The goal of this book is to provide advanced students and researchers a basic understanding of the kinin system and its role within the various organ systems. The authors of this book are experts in their fields, including a Nobel Laureate. |
תוכן
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| 7 | |
3 Kinin receptor signaling and regulation | 33 |
4 Animal models in the kinin field | 51 |
5 Drugs in the kallikreinkinin system | 69 |
6 Kallikreinkinin system in the brain | 85 |
7 The role of the renal kallikreinkinin system in physiology and pathology | 103 |
8 Kallikreinkinin system in the heart | 117 |
12 Kallikreinkinin system in reproductive organs | 187 |
13 The Kallikreinkinin system and thrombosis | 203 |
kallikreins and kinins in cancer | 217 |
15 Kallikreinkinin system in pain | 247 |
16 Kallikreinkinin system in inflammation | 261 |
17 Kallikreinkinin system in diabetes | 273 |
18 Kallikreinkinin system in angioedema | 289 |
19 Kinins in bacterial infections | 307 |
9 Kallikreinkinin system in the vessel wall | 137 |
modulators of skin homeostasis | 155 |
11 Kallikreinkinin system in the eye | 171 |
20 The kallikreinkinin system in parasitic infections | 321 |
21 Kallikreinkinin system in ischemic stroke and brain trauma | 337 |
מהדורות אחרות - הצג הכל
מונחים וביטויים נפוצים
ACE inhibitors activation agonist Alhenc-Gelas angioedema angiogenesis angiotensin angiotensin-converting enzyme B1 and B2 B1KO B2KO mice Bader Bascands Bhoola Biol blood pressure bradykinin B2 receptor bradykinin receptor brain C1-inhibitor Ca2+ Calixto cancer cardiac Chao Chem Clin clinical contact system converting enzyme cytokines deficiency diabetic nephropathy disease edema effects EGFR Emanueli endothelial cells enzyme inhibitors expression extracellular factor XII function FXII genetic human hyperalgesia Hypertension icatibant increased induced infection inflammation inflammatory inhibition involved ischemia ischemic Kakoki kallidin kallikrein gene kallikrein-kinin system keratinocytes kidney kinase kinin B1 receptor kinin receptors kininase kininogen KLK1 Leeb-Lundberg levels Madeddu mechanisms mediated molecular weight kininogen mRNA myocardial infarction neurons neutrophil nitric oxide pain pathway patients peptides permeability Pesquero Pharmacol Physiol plasma kallikrein polymorphism protease protein receptor antagonists regulation release renal response retinal role Schanstra signaling smooth muscle stimulation studies tissue kallikrein tumor upregulation vascular vitro vivo