Polymeric Site-specific Pharmacotherapy

Polymeric Site-Specific Pharmacotherapy Edited by A. J. Domb The Hebrew University of Jerusalem, Israel This unique edited volume provides a comprehensive overview of site-specific drug delivery using polymeric implant devices. From the basic concept of localized drug delivery to major applications under active research, the subject is treated from a theoretical and practical viewpoint. Coverage includes the design, development and applications of polymeric devices, including suitable polymers, delivery systems and mechanisms of drug release. Recent advances and ongoing research are included and many subjects are reviewed here for the first time. Contributed to by an international team of acknowledged experts, this volume will have broad appeal amongst researchers, both in academia and industry, with an interest in polymer chemistry, biopolymers, pharmaceutical analysis, pharmacology, bioengineering, and medical and organic chemistry. Contents include: Implantable Biodegradable Polymers for Site-specific Drug Delivery A. J. Domb; Drug Release and Tissue Distribution from a Polymer Implant M. L. Radomsky; Modelling of Drug Delivery to Brain Tissue G. D. Lapin; Polymer Conjugated Macromolecular Drugs for Tumor Specific Targeting H. Maeda; Drug Delivery to the Brain H. Brem, K. A. Walter, R. J. Tamargo, A. Olivi and R. Langer; Microparticulate Systems for Site-specific Therapy — Bone Marrow Targeting C. J. Porter, M. C. Davies, S. S. Davies and L. Illum; Drug Delivery to the Lung K. C. Meyer, W. Auerbach and R. Auerbach; Polymers for the Prevention of Surgical Adhesions A. J. Domb and D. Wiseman